Blar i forfatter "Yobuta, Rosalba"

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    • Independent External Validation of the METSSS Model Predicting Survival after Palliative Radiotherapy 

      Nieder, Carsten; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-26)
      Background/Aim: A validation of the recently published METSSS model (developed from a large US database) predicting survival after palliative radiotherapy was performed. METSSS includes age, sex, cancer type, localization of distant metastases, comorbidity, and radiotherapy site. Patients and Methods: Both 1- and 5-year survival was assessed in the validation cohort. Deviations between model-predicted ...

    • Initiation of systemic therapy during the last 30 days of life in patients with metastatic castration-resistant prostate cancer 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Pawinski, Adam; Yobuta, Rosalba; Norum, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      <b>Background/Aim</b>: Compared to intravenous taxane chemotherapy, newer orally-available and/or less toxic agents for metastatic castration-resistant prostate cancer (MCRPC) may be associated with higher likelihood of starting treatment in patients with adverse prognostic features and limited life expectancy. To test this hypothesis, we analyzed the rates of treatment initiation during the last ...

    • Palliative radiotherapy during the last month of life: Have COVID-19 recommendations led to reduced utilization? 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01)
      Background/Aim: The study aimed to evaluate practice changes in the time period of the early wave of the COVID-19 pandemic. Patients and Methods: This was a retrospective single institution study. We defined palliative radiotherapy (PRT) initiated before Saturday, March 14th as pre-COVID and PRT initiated later as during-COVID (through June 30th). Results: National COVID-19 recommendations ...

    • Patterns of treatment and outcome in patients with 20 or more brain metastases 

      Nieder, Carsten; Yobuta, Rosalba; Mannsåker, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01)
      <p><i>Background/Aim - </i>The aim of this study was to analyze the patterns of treatment and outcomes in patients with a large number of brain metastases, arbitrarily defined as 20 or more lesions. These patients are typically excluded from studies of focal brain treatment, e.g., surgery or radiosurgery, and might have a limited prognosis. <p><i>Patients and Methods - </i>This was a retrospective ...

    • Provider decision regret - a useful method for analysis of palliative thoracic re-irradiation for lung cancer? 

      Nieder, Carsten; Mannsåker, Bård; Yobuta, Rosalba; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-30)
      Background - The overall usefulness of palliative thoracic re-irradiation depends on the balance between efficacy, survival, and toxicity, and is difficult to judge from previous studies. In the absence of patient-reported data, we developed a method for provider decision regret that addresses the question “would we re-irradiate this patient again in light of the known outcome?” Furthermore, we ...

    • Risk factors for esophagitis after hypofractionated palliative (chemo) radiotherapy for non-small cell lung cancer 

      Nieder, Carsten; Imingen, Kristian S.; Mannsåker, Bård; Yobuta, Rosalba; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-01)
      <i>Introduction</i>: Esophagitis influences quality of life and might cause treatment interruption and hospitalization. Previous studies of risk factors focused on curative treatment for non-small cell lung cancer (NSCLC), which often involves concomitant chemoradiation (CRT). Given the uncertainty around extrapolation of dose constraints, we analyzed risk factors in patients treated with hypofractionated ...

    • Validation of a graded prognostic model in patients with brain metastases treated with whole-brain radiotherapy instead of radiosurgery 

      Nieder, Carsten; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05)
      Background/Aim: The aim of this study was to analyze the survival predictions obtained from a recent graded prognostic model developed and validated in Japan.<p><p> Patients and Methods: This was a retrospective single-institution analysis of 249 patients, managed with whole-brain radiotherapy for brain metastases. The sum of scores was calculated as in the Japanese study. The following parameters ...